Logistic regression - overview

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Logistic regression
Friedman test
Independent variablesIndependent variable
One or more quantitative of interval or ratio level and/or one or more categorical with independent groups, transformed into code variablesOne within subject factor ($\geq 2$ related groups)
Dependent variableDependent variable
One categorical with 2 independent groupsOne of ordinal level
Null hypothesisNull hypothesis
Model chi-squared test for the complete regression model:
  • $\beta_1 = \beta_2 = \ldots = \beta_K = 0$
Wald test for individual regression coefficient $\beta_k$:
  • $\beta_k = 0$
    or in terms of odds ratio:
  • $e^{\beta_k} = 1$
Likelihood ratio chi-squared test for individual regression coefficient $\beta_k$:
  • $\beta_k = 0$
    or in terms of odds ratio:
  • $e^{\beta_k} = 1$
in the regression equation $ \ln \big(\frac{\pi_{y = 1}}{1 - \pi_{y = 1}} \big) = \beta_0 + \beta_1 \times x_1 + \beta_2 \times x_2 + \ldots + \beta_K \times x_K $
The scores in any of the related groups are not systematically higher or lower than the scores in any of the other related groups

Note: usually, the related groups are the different measurement points

Several different formulations of the null hypothesis can be found in the literature, and we do not agree with all of them. Make sure you (also) learn the one that is given in your text book or by your teacher.
Alternative hypothesisAlternative hypothesis
Model chi-squared test for the complete regression model:
  • not all population regression coefficients are 0
Wald test for individual $\beta_k$:
  • $\beta_k \neq 0$
    or in terms of odds ratio:
  • $e^{\beta_k} \neq 1$
    If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$ (see 'Test statistic'), also one sided alternatives can be tested:
  • right sided: $\beta_k > 0$
  • left sided: $\beta_k < 0$
Likelihood ratio chi-squared test for individual $\beta_k$:
  • $\beta_k \neq 0$
    or in terms of odds ratio:
  • $e^{\beta_k} \neq 1$
The scores in some of the related groups are systematically higher or lower than the scores in other related groups
AssumptionsAssumptions
  • In the population, the relationship between the independent variables and the log odds $\ln (\frac{\pi_{y=1}}{1 - \pi_{y=1}})$ is linear
  • The residuals are independent of one another
Often ignored additional assumption:
  • Variables are measured without error
Also pay attention to:
  • Multicollinearity
  • Outliers
Sample of 'blocks' (usually the subjects) is a simple random sample from the population. That is, blocks are independent of one another
Test statisticTest statistic
Model chi-squared test for the complete regression model:
  • $X^2 = D_{null} - D_K = \mbox{null deviance} - \mbox{model deviance} $
    $D_{null}$, the null deviance, is conceptually similar to the total variance of the dependent variable in OLS regression analysis. $D_K$, the model deviance, is conceptually similar to the residual variance in OLS regression analysis.
Wald test for individual $\beta_k$:
The wald statistic can be defined in two ways:
  • Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$
  • Wald $ = \dfrac{b_k}{SE_{b_k}}$
SPSS uses the first definition

Likelihood ratio chi-squared test for individual $\beta_k$:
  • $X^2 = D_{K-1} - D_K$
    $D_{K-1}$ is the model deviance, where independent variable $k$ is excluded from the model. $D_{K}$ is the model deviance, where independent variable $k$ is included in the model.
$Q = \dfrac{12}{N \times k(k + 1)} \sum R^2_i - 3 \times N(k + 1)$

Here $N$ is the number of 'blocks' (usually the subjects - so if you have 4 repeated measurements for 60 subjects, $N$ equals 60), $k$ is the number of related groups (usually the number of repeated measurements), and $R_i$ is the sum of ranks in group $i$.

Remember that multiplication precedes addition, so first compute $\frac{12}{N \times k(k + 1)} \times \sum R^2_i$ and then subtract $3 \times N(k + 1)$.

Note: if ties are present in the data, the formula for $Q$ is more complicated.
Sampling distribution of $X^2$ and of the Wald statistic if H0 were trueSampling distribution of $Q$ if H0 were true
Sampling distribution of $X^2$, as computed in the model chi-squared test for the complete model:
  • chi-squared distribution with $K$ (number of independent variables) degrees of freedom
Sampling distribution of the Wald statistic:
  • If defined as Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$: approximately a chi-squared distribution with 1 degree of freedom
  • If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$: approximately a standard normal distribution
Sampling distribution of $X^2$, as computed in the likelihood ratio chi-squared test for individual $\beta_k$:
  • chi-squared distribution with 1 degree of freedom
If the number of blocks $N$ is large, approximately the chi-squared distribution with $k - 1$ degrees of freedom.

For small samples, the exact distribution of $Q$ should be used.
Significant?Significant?
For the model chi-squared test for the complete regression model and likelihood ratio chi-squared test for individual $\beta_k$:
  • Check if $X^2$ observed in sample is equal to or larger than critical value $X^{2*}$ or
  • Find $p$ value corresponding to observed $X^2$ and check if it is equal to or smaller than $\alpha$
For the Wald test:
  • If defined as Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$: same procedure as for the chi-squared tests. Wald can be interpret as $X^2$
  • If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$: same procedure as for any $z$ test. Wald can be interpreted as $z$.
If the number of blocks $N$ is large, the table with critical $X^2$ values can be used. If we denote $X^2 = Q$:
  • Check if $X^2$ observed in sample is equal to or larger than critical value $X^{2*}$ or
  • Find $p$ value corresponding to observed $X^2$ and check if it is equal to or smaller than $\alpha$
Wald-type approximate $C\%$ confidence interval for $\beta_k$n.a.
$b_k \pm z^* \times SE_{b_k}$
where $z^*$ is the value under the normal curve with the area $C / 100$ between $-z^*$ and $z^*$ (e.g. $z^*$ = 1.96 for a 95% confidence interval)
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Goodness of fit measure $R^2_L$n.a.
$R^2_L = \dfrac{D_{null} - D_K}{D_{null}}$
There are several other goodness of fit measures in logistic regression. In logistic regression, there is no single agreed upon measure of goodness of fit.
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Example contextExample context
Can body mass index, stress level, and gender predict whether people get diagnosed with diabetes?Is there a difference in depression level between measurement point 1 (pre-intervention), measurement point 2 (1 week post-interventiom), and measurement point 3 (6 weeks post-intervention)?
SPSSSPSS
Analyze > Regression > Binary Logistic...
  • Put your dependent variable in the box below Dependent and your independent (predictor) variables in the box below Covariate(s)
Analyze > Nonparametric Tests > Legacy Dialogs > K Related Samples...
  • Put the $k$ variables containing the scores for the $k$ related groups in the white box below Test Variables
  • Under Test Type, select the Friedman test
JamoviJamovi
Regression > 2 Outcomes - Binomial
  • Put your dependent variable in the box below Dependent Variable and your independent variables of interval/ratio level in the box below Covariates
  • If you also have code (dummy) variables as independent variables, you can put these in the box below Covariates as well
  • Instead of transforming your categorical independent variable(s) into code variables, you can also put the untransformed categorical independent variables in the box below Factors. Jamovi will then make the code variables for you 'behind the scenes'
ANOVA > Repeated Measures ANOVA - Friedman
  • Put the $k$ variables containing the scores for the $k$ related groups in the box below Measures
Practice questionsPractice questions