# Logistic regression - overview

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Logistic regression
Two sample $t$ test - equal variances not assumed
Mann-Whitney-Wilcoxon test
Independent variablesIndependent variableIndependent variable
One or more quantitative of interval or ratio level and/or one or more categorical with independent groups, transformed into code variablesOne categorical with 2 independent groupsOne categorical with 2 independent groups
Dependent variableDependent variableDependent variable
One categorical with 2 independent groupsOne quantitative of interval or ratio levelOne of ordinal level
Null hypothesisNull hypothesisNull hypothesis
Model chi-squared test for the complete regression model:
• $\beta_1 = \beta_2 = \ldots = \beta_K = 0$
Wald test for individual regression coefficient $\beta_k$:
• $\beta_k = 0$
or in terms of odds ratio:
• $e^{\beta_k} = 1$
Likelihood ratio chi-squared test for individual regression coefficient $\beta_k$:
• $\beta_k = 0$
or in terms of odds ratio:
• $e^{\beta_k} = 1$
in the regression equation $\ln \big(\frac{\pi_{y = 1}}{1 - \pi_{y = 1}} \big) = \beta_0 + \beta_1 \times x_1 + \beta_2 \times x_2 + \ldots + \beta_K \times x_K$
$\mu_1 = \mu_2$
$\mu_1$ is the unknown mean in population 1, $\mu_2$ is the unknown mean in population 2
If the dependent variable is measured on a continuous scale and the shape of the distribution of the dependent variable is the same in both populations:
• The median in population 1 is equal to the median in population 2
Else:
Formulation 1:
• The scores in population 1 are not systematically higher or lower than the scores in population 2
Formulation 2:
• P(an observation from population 1 exceeds an observation from population 2) = P(an observation from population 2 exceeds observation from population 1)
Several different formulations of the null hypothesis can be found in the literature, and we do not agree with all of them. Make sure you (also) learn the one that is given in your text book or by your teacher.
Alternative hypothesisAlternative hypothesisAlternative hypothesis
Model chi-squared test for the complete regression model:
• not all population regression coefficients are 0
Wald test for individual $\beta_k$:
• $\beta_k \neq 0$
or in terms of odds ratio:
• $e^{\beta_k} \neq 1$
If defined as Wald $= \dfrac{b_k}{SE_{b_k}}$ (see 'Test statistic'), also one sided alternatives can be tested:
• right sided: $\beta_k > 0$
• left sided: $\beta_k < 0$
Likelihood ratio chi-squared test for individual $\beta_k$:
• $\beta_k \neq 0$
or in terms of odds ratio:
• $e^{\beta_k} \neq 1$
Two sided: $\mu_1 \neq \mu_2$
Right sided: $\mu_1 > \mu_2$
Left sided: $\mu_1 < \mu_2$
If the dependent variable is measured on a continuous scale and the shape of the distribution of the dependent variable is the same in both populations:
• Two sided: the median in population 1 is not equal to the median in population 2
• Right sided: the median in population 1 is larger than the median in population 2
• Left sided: the median in population 1 is smaller than the median in population 2
Else:
Formulation 1:
• Two sided: The scores in population 1 are systematically higher or lower than the scores in population 2
• Right sided: The scores in population 1 are systematically higher than the scores in population 2
• Left sided: The scores in population 1 are systematically lower than the scores in population 2
Formulation 2:
• Two sided: P(an observation from population 1 exceeds an observation from population 2) $\neq$ P(an observation from population 2 exceeds an observation from population 1)
• Right sided: P(an observation from population 1 exceeds an observation from population 2) > P(an observation from population 2 exceeds an observation from population 1)
• Left sided: P(an observation from population 1 exceeds an observation from population 2) < P(an observation from population 2 exceeds an observation from population 1)
AssumptionsAssumptionsAssumptions
• In the population, the relationship between the independent variables and the log odds $\ln (\frac{\pi_{y=1}}{1 - \pi_{y=1}})$ is linear
• The residuals are independent of one another
• Variables are measured without error
Also pay attention to:
• Multicollinearity
• Outliers
• Within each population, the scores on the dependent variable are normally distributed
• Group 1 sample is a simple random sample (SRS) from population 1, group 2 sample is an independent SRS from population 2. That is, within and between groups, observations are independent of one another
Group 1 sample is a simple random sample (SRS) from population 1, group 2 sample is an independent SRS from population 2. That is, within and between groups, observations are independent of one another
Test statisticTest statisticTest statistic
Model chi-squared test for the complete regression model:
• $X^2 = D_{null} - D_K = \mbox{null deviance} - \mbox{model deviance}$
$D_{null}$, the null deviance, is conceptually similar to the total variance of the dependent variable in OLS regression analysis. $D_K$, the model deviance, is conceptually similar to the residual variance in OLS regression analysis.
Wald test for individual $\beta_k$:
The wald statistic can be defined in two ways:
• Wald $= \dfrac{b_k^2}{SE^2_{b_k}}$
• Wald $= \dfrac{b_k}{SE_{b_k}}$
SPSS uses the first definition

Likelihood ratio chi-squared test for individual $\beta_k$:
• $X^2 = D_{K-1} - D_K$
$D_{K-1}$ is the model deviance, where independent variable $k$ is excluded from the model. $D_{K}$ is the model deviance, where independent variable $k$ is included in the model.
$t = \dfrac{(\bar{y}_1 - \bar{y}_2) - 0}{\sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}} = \dfrac{\bar{y}_1 - \bar{y}_2}{\sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}}$
$\bar{y}_1$ is the sample mean in group 1, $\bar{y}_2$ is the sample mean in group 2, $s^2_1$ is the sample variance in group 1, $s^2_2$ is the sample variance in group 2, $n_1$ is the sample size of group 1, $n_2$ is the sample size of group 2. The 0 represents the difference in population means according to H0.

The denominator $\sqrt{\frac{s^2_1}{n_1} + \frac{s^2_2}{n_2}}$ is the standard error of the sampling distribution of $\bar{y}_1 - \bar{y}_2$. The $t$ value indicates how many standard errors $\bar{y}_1 - \bar{y}_2$ is removed from 0.

Note: we could just as well compute $\bar{y}_2 - \bar{y}_1$ in the numerator, but then the left sided alternative becomes $\mu_2 < \mu_1$, and the right sided alternative becomes $\mu_2 > \mu_1$
Two different types of test statistics can be used; both will result in the same test outcome. The first is the Wilcoxon rank sum statistic $W$:
The second type of test statistic is the Mann-Whitney $U$ statistic:
• $U = W - \dfrac{n_1(n_1 + 1)}{2}$
where $n_1$ is the sample size of group 1

Note: we could just as well base W and U on group 2. This would only 'flip' the right and left sided alternative hypotheses. Also, tables with critical values for $U$ are often based on the smaller of $U$ for group 1 and for group 2.
Sampling distribution of $X^2$ and of the Wald statistic if H0 were trueSampling distribution of $t$ if H0 were trueSampling distribution of $W$ and of $U$ if H0 were true
Sampling distribution of $X^2$, as computed in the model chi-squared test for the complete model:
• chi-squared distribution with $K$ (number of independent variables) degrees of freedom
Sampling distribution of the Wald statistic:
• If defined as Wald $= \dfrac{b_k^2}{SE^2_{b_k}}$: approximately a chi-squared distribution with 1 degree of freedom
• If defined as Wald $= \dfrac{b_k}{SE_{b_k}}$: approximately a standard normal distribution
Sampling distribution of $X^2$, as computed in the likelihood ratio chi-squared test for individual $\beta_k$:
• chi-squared distribution with 1 degree of freedom
Approximately a $t$ distribution with $k$ degrees of freedom, with $k$ equal to
$k = \dfrac{\Bigg(\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}\Bigg)^2}{\dfrac{1}{n_1 - 1} \Bigg(\dfrac{s^2_1}{n_1}\Bigg)^2 + \dfrac{1}{n_2 - 1} \Bigg(\dfrac{s^2_2}{n_2}\Bigg)^2}$
or
$k$ = the smaller of $n_1$ - 1 and $n_2$ - 1

First definition of $k$ is used by computer programs, second definition is often used for hand calculations

Sampling distribution of $W$:
For large samples, $W$ is approximately normally distributed with mean $\mu_W$ and standard deviation $\sigma_W$ if the null hypothesis were true. Here \begin{aligned} \mu_W &= \dfrac{n_1(n_1 + n_2 + 1)}{2}\\ \sigma_W &= \sqrt{\dfrac{n_1 n_2(n_1 + n_2 + 1)}{12}} \end{aligned} Hence, for large samples, the standardized test statistic $$z_W = \dfrac{W - \mu_W}{\sigma_W}\\$$ follows approximately a standard normal distribution if the null hypothesis were true. Note that if your $W$ value is based on group 2, $\mu_W$ becomes $\frac{n_2(n_1 + n_2 + 1)}{2}$.

Sampling distribution of $U$:
For large samples, $U$ is approximately normally distributed with mean $\mu_U$ and standard deviation $\sigma_U$ if the null hypothesis were true. Here \begin{aligned} \mu_U &= \dfrac{n_1 n_2}{2}\\ \sigma_U &= \sqrt{\dfrac{n_1 n_2(n_1 + n_2 + 1)}{12}} \end{aligned} Hence, for large samples, the standardized test statistic $$z_U = \dfrac{U - \mu_U}{\sigma_U}\\$$ follows approximately a standard normal distribution if the null hypothesis were true.

For small samples, the exact distribution of $W$ or $U$ should be used.

Note: the formula for the standard deviations $\sigma_W$ and $\sigma_U$ is more complicated if ties are present in the data.
Significant?Significant?Significant?
For the model chi-squared test for the complete regression model and likelihood ratio chi-squared test for individual $\beta_k$:
• Check if $X^2$ observed in sample is equal to or larger than critical value $X^{2*}$ or
• Find $p$ value corresponding to observed $X^2$ and check if it is equal to or smaller than $\alpha$
For the Wald test:
• If defined as Wald $= \dfrac{b_k^2}{SE^2_{b_k}}$: same procedure as for the chi-squared tests. Wald can be interpret as $X^2$
• If defined as Wald $= \dfrac{b_k}{SE_{b_k}}$: same procedure as for any $z$ test. Wald can be interpreted as $z$.
Two sided:
Right sided:
Left sided:
For large samples, the table for standard normal probabilities can be used:
Two sided:
Right sided:
Left sided:
Wald-type approximate $C\%$ confidence interval for $\beta_k$Approximate $C\%$ confidence interval for $\mu_1 - \mu_2$n.a.
$b_k \pm z^* \times SE_{b_k}$
where $z^*$ is the value under the normal curve with the area $C / 100$ between $-z^*$ and $z^*$ (e.g. $z^*$ = 1.96 for a 95% confidence interval)
$(\bar{y}_1 - \bar{y}_2) \pm t^* \times \sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}$
where the critical value $t^*$ is the value under the $t_{k}$ distribution with the area $C / 100$ between $-t^*$ and $t^*$ (e.g. $t^*$ = 2.086 for a 95% confidence interval when df = 20)

The confidence interval for $\mu_1 - \mu_2$ can also be used as significance test.
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Goodness of fit measure $R^2_L$n.a.n.a.
$R^2_L = \dfrac{D_{null} - D_K}{D_{null}}$
There are several other goodness of fit measures in logistic regression. In logistic regression, there is no single agreed upon measure of goodness of fit.
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n.a.Visual representationn.a.
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n.a.n.a.Equivalent to
--If no ties in the data: two sided Mann-Whitney-Wilcoxon test is equivalent to Kruskal-Wallis test with an independent variable with 2 levels ($I = 2$)
Example contextExample contextExample context
Can body mass index, stress level, and gender predict whether people get diagnosed with diabetes?Is the average mental health score different between men and women?Do men tend to score higher on social economic status than women?
SPSSSPSSSPSS
Analyze > Regression > Binary Logistic...
• Put your dependent variable in the box below Dependent and your independent (predictor) variables in the box below Covariate(s)
Analyze > Compare Means > Independent-Samples T Test...
• Put your dependent (quantitative) variable in the box below Test Variable(s) and your independent (grouping) variable in the box below Grouping Variable
• Click on the Define Groups... button. If you can't click on it, first click on the grouping variable so its background turns yellow
• Fill in the value you have used to indicate your first group in the box next to Group 1, and the value you have used to indicate your second group in the box next to Group 2
• Continue and click OK
Analyze > Nonparametric Tests > Legacy Dialogs > 2 Independent Samples...
• Put your dependent variable in the box below Test Variable List and your independent (grouping) variable in the box below Grouping Variable
• Click on the Define Groups... button. If you can't click on it, first click on the grouping variable so its background turns yellow
• Fill in the value you have used to indicate your first group in the box next to Group 1, and the value you have used to indicate your second group in the box next to Group 2
• Continue and click OK
JamoviJamoviJamovi
Regression > 2 Outcomes - Binomial
• Put your dependent variable in the box below Dependent Variable and your independent variables of interval/ratio level in the box below Covariates
• If you also have code (dummy) variables as independent variables, you can put these in the box below Covariates as well
• Instead of transforming your categorical independent variable(s) into code variables, you can also put the untransformed categorical independent variables in the box below Factors. Jamovi will then make the code variables for you 'behind the scenes'
T-Tests > Independent Samples T-Test
• Put your dependent (quantitative) variable in the box below Dependent Variables and your independent (grouping) variable in the box below Grouping Variable
• Under Tests, select Welch's
• Under Hypothesis, select your alternative hypothesis
T-Tests > Independent Samples T-Test
• Put your dependent variable in the box below Dependent Variables and your independent (grouping) variable in the box below Grouping Variable
• Under Tests, select Mann-Whitney U
• Under Hypothesis, select your alternative hypothesis
Practice questionsPractice questionsPractice questions