Two sample t test - equal variances not assumed - overview

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Two sample $t$ test - equal variances not assumed
Two sample $t$ test - equal variances assumed
McNemar's test
Logistic regression
Independent/grouping variableIndependent/grouping variableIndependent variableIndependent variables
One categorical with 2 independent groupsOne categorical with 2 independent groups2 paired groupsOne or more quantitative of interval or ratio level and/or one or more categorical with independent groups, transformed into code variables
Dependent variableDependent variableDependent variableDependent variable
One quantitative of interval or ratio levelOne quantitative of interval or ratio levelOne categorical with 2 independent groupsOne categorical with 2 independent groups
Null hypothesisNull hypothesisNull hypothesisNull hypothesis
H0: $\mu_1 = \mu_2$

Here $\mu_1$ is the population mean for group 1, and $\mu_2$ is the population mean for group 2.
H0: $\mu_1 = \mu_2$

Here $\mu_1$ is the population mean for group 1, and $\mu_2$ is the population mean for group 2.

Let's say that the scores on the dependent variable are scored 0 and 1. Then for each pair of scores, the data allow four options:

  1. First score of pair is 0, second score of pair is 0
  2. First score of pair is 0, second score of pair is 1 (switched)
  3. First score of pair is 1, second score of pair is 0 (switched)
  4. First score of pair is 1, second score of pair is 1
The null hypothesis H0 is that for each pair of scores, P(first score of pair is 0 while second score of pair is 1) = P(first score of pair is 1 while second score of pair is 0). That is, the probability that a pair of scores switches from 0 to 1 is the same as the probability that a pair of scores switches from 1 to 0.

Other formulations of the null hypothesis are:

  • H0: $\pi_1 = \pi_2$, where $\pi_1$ is the population proportion of ones for the first paired group and $\pi_2$ is the population proportion of ones for the second paired group
  • H0: for each pair of scores, P(first score of pair is 1) = P(second score of pair is 1)

Model chi-squared test for the complete regression model:
  • H0: $\beta_1 = \beta_2 = \ldots = \beta_K = 0$
Wald test for individual regression coefficient $\beta_k$:
  • H0: $\beta_k = 0$
    or in terms of odds ratio:
  • H0: $e^{\beta_k} = 1$
Likelihood ratio chi-squared test for individual regression coefficient $\beta_k$:
  • H0: $\beta_k = 0$
    or in terms of odds ratio:
  • H0: $e^{\beta_k} = 1$
in the regression equation $ \ln \big(\frac{\pi_{y = 1}}{1 - \pi_{y = 1}} \big) = \beta_0 + \beta_1 \times x_1 + \beta_2 \times x_2 + \ldots + \beta_K \times x_K $. Here $ x_i$ represents independent variable $ i$, $\beta_i$ is the regression weight for independent variable $ x_i$, and $\pi_{y = 1}$ represents the true probability that the dependent variable $ y = 1$ (or equivalently, the proportion of $ y = 1$ in the population) given the scores on the independent variables.
Alternative hypothesisAlternative hypothesisAlternative hypothesisAlternative hypothesis
H1 two sided: $\mu_1 \neq \mu_2$
H1 right sided: $\mu_1 > \mu_2$
H1 left sided: $\mu_1 < \mu_2$
H1 two sided: $\mu_1 \neq \mu_2$
H1 right sided: $\mu_1 > \mu_2$
H1 left sided: $\mu_1 < \mu_2$

The alternative hypothesis H1 is that for each pair of scores, P(first score of pair is 0 while second score of pair is 1) $\neq$ P(first score of pair is 1 while second score of pair is 0). That is, the probability that a pair of scores switches from 0 to 1 is not the same as the probability that a pair of scores switches from 1 to 0.

Other formulations of the alternative hypothesis are:

  • H1: $\pi_1 \neq \pi_2$
  • H1: for each pair of scores, P(first score of pair is 1) $\neq$ P(second score of pair is 1)

Model chi-squared test for the complete regression model:
  • H1: not all population regression coefficients are 0
Wald test for individual regression coefficient $\beta_k$:
  • H1: $\beta_k \neq 0$
    or in terms of odds ratio:
  • H1: $e^{\beta_k} \neq 1$
    If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$ (see 'Test statistic'), also one sided alternatives can be tested:
  • H1 right sided: $\beta_k > 0$
  • H1 left sided: $\beta_k < 0$
Likelihood ratio chi-squared test for individual regression coefficient $\beta_k$:
  • H1: $\beta_k \neq 0$
    or in terms of odds ratio:
  • H1: $e^{\beta_k} \neq 1$
AssumptionsAssumptionsAssumptionsAssumptions
  • Within each population, the scores on the dependent variable are normally distributed
  • Group 1 sample is a simple random sample (SRS) from population 1, group 2 sample is an independent SRS from population 2. That is, within and between groups, observations are independent of one another
  • Within each population, the scores on the dependent variable are normally distributed
  • The standard deviation of the scores on the dependent variable is the same in both populations: $\sigma_1 = \sigma_2$
  • Group 1 sample is a simple random sample (SRS) from population 1, group 2 sample is an independent SRS from population 2. That is, within and between groups, observations are independent of one another
  • Sample of pairs is a simple random sample from the population of pairs. That is, pairs are independent of one another
  • In the population, the relationship between the independent variables and the log odds $\ln (\frac{\pi_{y=1}}{1 - \pi_{y=1}})$ is linear
  • The residuals are independent of one another
Often ignored additional assumption:
  • Variables are measured without error
Also pay attention to:
  • Multicollinearity
  • Outliers
Test statisticTest statisticTest statisticTest statistic
$t = \dfrac{(\bar{y}_1 - \bar{y}_2) - 0}{\sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}} = \dfrac{\bar{y}_1 - \bar{y}_2}{\sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}}$
Here $\bar{y}_1$ is the sample mean in group 1, $\bar{y}_2$ is the sample mean in group 2, $s^2_1$ is the sample variance in group 1, $s^2_2$ is the sample variance in group 2, $n_1$ is the sample size of group 1, and $n_2$ is the sample size of group 2. The 0 represents the difference in population means according to the null hypothesis.

The denominator $\sqrt{\frac{s^2_1}{n_1} + \frac{s^2_2}{n_2}}$ is the standard error of the sampling distribution of $\bar{y}_1 - \bar{y}_2$. The $t$ value indicates how many standard errors $\bar{y}_1 - \bar{y}_2$ is removed from 0.

Note: we could just as well compute $\bar{y}_2 - \bar{y}_1$ in the numerator, but then the left sided alternative becomes $\mu_2 < \mu_1$, and the right sided alternative becomes $\mu_2 > \mu_1$.
$t = \dfrac{(\bar{y}_1 - \bar{y}_2) - 0}{s_p\sqrt{\dfrac{1}{n_1} + \dfrac{1}{n_2}}} = \dfrac{\bar{y}_1 - \bar{y}_2}{s_p\sqrt{\dfrac{1}{n_1} + \dfrac{1}{n_2}}}$
Here $\bar{y}_1$ is the sample mean in group 1, $\bar{y}_2$ is the sample mean in group 2, $s_p$ is the pooled standard deviation, $n_1$ is the sample size of group 1, and $n_2$ is the sample size of group 2. The 0 represents the difference in population means according to the null hypothesis.

The denominator $s_p\sqrt{\dfrac{1}{n_1} + \dfrac{1}{n_2}}$ is the standard error of the sampling distribution of $\bar{y}_1 - \bar{y}_2$. The $t$ value indicates how many standard errors $\bar{y}_1 - \bar{y}_2$ is removed from 0.

Note: we could just as well compute $\bar{y}_2 - \bar{y}_1$ in the numerator, but then the left sided alternative becomes $\mu_2 < \mu_1$, and the right sided alternative becomes $\mu_2 > \mu_1$.
$X^2 = \dfrac{(b - c)^2}{b + c}$
Here $b$ is the number of pairs in the sample for which the first score is 0 while the second score is 1, and $c$ is the number of pairs in the sample for which the first score is 1 while the second score is 0.
Model chi-squared test for the complete regression model:
  • $X^2 = D_{null} - D_K = \mbox{null deviance} - \mbox{model deviance} $
    $D_{null}$, the null deviance, is conceptually similar to the total variance of the dependent variable in OLS regression analysis. $D_K$, the model deviance, is conceptually similar to the residual variance in OLS regression analysis.
Wald test for individual $\beta_k$:
The wald statistic can be defined in two ways:
  • Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$
  • Wald $ = \dfrac{b_k}{SE_{b_k}}$
SPSS uses the first definition.

Likelihood ratio chi-squared test for individual $\beta_k$:
  • $X^2 = D_{K-1} - D_K$
    $D_{K-1}$ is the model deviance, where independent variable $k$ is excluded from the model. $D_{K}$ is the model deviance, where independent variable $k$ is included in the model.
n.a.Pooled standard deviationn.a.n.a.
-$s_p = \sqrt{\dfrac{(n_1 - 1) \times s^2_1 + (n_2 - 1) \times s^2_2}{n_1 + n_2 - 2}}$--
Sampling distribution of $t$ if H0 were trueSampling distribution of $t$ if H0 were trueSampling distribution of $X^2$ if H0 were trueSampling distribution of $X^2$ and of the Wald statistic if H0 were true
Approximately the $t$ distribution with $k$ degrees of freedom, with $k$ equal to
$k = \dfrac{\Bigg(\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}\Bigg)^2}{\dfrac{1}{n_1 - 1} \Bigg(\dfrac{s^2_1}{n_1}\Bigg)^2 + \dfrac{1}{n_2 - 1} \Bigg(\dfrac{s^2_2}{n_2}\Bigg)^2}$
or
$k$ = the smaller of $n_1$ - 1 and $n_2$ - 1

First definition of $k$ is used by computer programs, second definition is often used for hand calculations.
$t$ distribution with $n_1 + n_2 - 2$ degrees of freedom

If $b + c$ is large enough (say, > 20), approximately the chi-squared distribution with 1 degree of freedom.

If $b + c$ is small, the Binomial($n$, $P$) distribution should be used, with $n = b + c$ and $P = 0.5$. In that case the test statistic becomes equal to $b$.

Sampling distribution of $X^2$, as computed in the model chi-squared test for the complete model:
  • chi-squared distribution with $K$ (number of independent variables) degrees of freedom
Sampling distribution of the Wald statistic:
  • If defined as Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$: approximately the chi-squared distribution with 1 degree of freedom
  • If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$: approximately the standard normal distribution
Sampling distribution of $X^2$, as computed in the likelihood ratio chi-squared test for individual $\beta_k$:
  • chi-squared distribution with 1 degree of freedom
Significant?Significant?Significant?Significant?
Two sided: Right sided: Left sided: Two sided: Right sided: Left sided: For test statistic $X^2$:
  • Check if $X^2$ observed in sample is equal to or larger than critical value $X^{2*}$ or
  • Find $p$ value corresponding to observed $X^2$ and check if it is equal to or smaller than $\alpha$
If $b + c$ is small, the table for the binomial distribution should be used, with as test statistic $b$:
  • Check if $b$ observed in sample is in the rejection region or
  • Find two sided $p$ value corresponding to observed $b$ and check if it is equal to or smaller than $\alpha$
For the model chi-squared test for the complete regression model and likelihood ratio chi-squared test for individual $\beta_k$:
  • Check if $X^2$ observed in sample is equal to or larger than critical value $X^{2*}$ or
  • Find $p$ value corresponding to observed $X^2$ and check if it is equal to or smaller than $\alpha$
For the Wald test:
  • If defined as Wald $ = \dfrac{b_k^2}{SE^2_{b_k}}$: same procedure as for the chi-squared tests. Wald can be interpret as $X^2$
  • If defined as Wald $ = \dfrac{b_k}{SE_{b_k}}$: same procedure as for any $z$ test. Wald can be interpreted as $z$.
Approximate $C\%$ confidence interval for $\mu_1 - \mu_2$$C\%$ confidence interval for $\mu_1 - \mu_2$n.a.Wald-type approximate $C\%$ confidence interval for $\beta_k$
$(\bar{y}_1 - \bar{y}_2) \pm t^* \times \sqrt{\dfrac{s^2_1}{n_1} + \dfrac{s^2_2}{n_2}}$
where the critical value $t^*$ is the value under the $t_{k}$ distribution with the area $C / 100$ between $-t^*$ and $t^*$ (e.g. $t^*$ = 2.086 for a 95% confidence interval when df = 20).

The confidence interval for $\mu_1 - \mu_2$ can also be used as significance test.
$(\bar{y}_1 - \bar{y}_2) \pm t^* \times s_p\sqrt{\dfrac{1}{n_1} + \dfrac{1}{n_2}}$
where the critical value $t^*$ is the value under the $t_{n_1 + n_2 - 2}$ distribution with the area $C / 100$ between $-t^*$ and $t^*$ (e.g. $t^*$ = 2.086 for a 95% confidence interval when df = 20).

The confidence interval for $\mu_1 - \mu_2$ can also be used as significance test.
-$b_k \pm z^* \times SE_{b_k}$
where the critical value $z^*$ is the value under the normal curve with the area $C / 100$ between $-z^*$ and $z^*$ (e.g. $z^*$ = 1.96 for a 95% confidence interval).
n.a.Effect sizen.a.Goodness of fit measure $R^2_L$
-Cohen's $d$:
Standardized difference between the mean in group $1$ and in group $2$: $$d = \frac{\bar{y}_1 - \bar{y}_2}{s_p}$$ Cohen's $d$ indicates how many standard deviations $s_p$ the two sample means are removed from each other.
-$R^2_L = \dfrac{D_{null} - D_K}{D_{null}}$
There are several other goodness of fit measures in logistic regression. In logistic regression, there is no single agreed upon measure of goodness of fit.
Visual representationVisual representationn.a.n.a.
Two sample t test - equal variances not assumed
Two sample t test - equal variances assumed
--
n.a.Equivalent toEquivalent ton.a.
-One way ANOVA with an independent variable with 2 levels ($I$ = 2):
  • two sided two sample $t$ test is equivalent to ANOVA $F$ test when $I$ = 2
  • two sample $t$ test is equivalent to $t$ test for contrast when $I$ = 2
  • two sample $t$ test is equivalent to $t$ test multiple comparisons when $I$ = 2
OLS regression with one categorical independent variable with 2 levels:
  • two sided two sample $t$ test is equivalent to $F$ test regression model
  • two sample $t$ test is equivalent to $t$ test for regression coefficient $\beta_1$
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Example contextExample contextExample contextExample context
Is the average mental health score different between men and women?Is the average mental health score different between men and women? Assume that in the population, the standard deviation of mental health scores is equal amongst men and women.Does a tv documentary about spiders change whether people are afraid (yes/no) of spiders?Can body mass index, stress level, and gender predict whether people get diagnosed with diabetes?
SPSSSPSSSPSSSPSS
Analyze > Compare Means > Independent-Samples T Test...
  • Put your dependent (quantitative) variable in the box below Test Variable(s) and your independent (grouping) variable in the box below Grouping Variable
  • Click on the Define Groups... button. If you can't click on it, first click on the grouping variable so its background turns yellow
  • Fill in the value you have used to indicate your first group in the box next to Group 1, and the value you have used to indicate your second group in the box next to Group 2
  • Continue and click OK
Analyze > Compare Means > Independent-Samples T Test...
  • Put your dependent (quantitative) variable in the box below Test Variable(s) and your independent (grouping) variable in the box below Grouping Variable
  • Click on the Define Groups... button. If you can't click on it, first click on the grouping variable so its background turns yellow
  • Fill in the value you have used to indicate your first group in the box next to Group 1, and the value you have used to indicate your second group in the box next to Group 2
  • Continue and click OK
Analyze > Nonparametric Tests > Legacy Dialogs > 2 Related Samples...
  • Put the two paired variables in the boxes below Variable 1 and Variable 2
  • Under Test Type, select the McNemar test
Analyze > Regression > Binary Logistic...
  • Put your dependent variable in the box below Dependent and your independent (predictor) variables in the box below Covariate(s)
JamoviJamoviJamoviJamovi
T-Tests > Independent Samples T-Test
  • Put your dependent (quantitative) variable in the box below Dependent Variables and your independent (grouping) variable in the box below Grouping Variable
  • Under Tests, select Welch's
  • Under Hypothesis, select your alternative hypothesis
T-Tests > Independent Samples T-Test
  • Put your dependent (quantitative) variable in the box below Dependent Variables and your independent (grouping) variable in the box below Grouping Variable
  • Under Tests, select Student's (selected by default)
  • Under Hypothesis, select your alternative hypothesis
Frequencies > Paired Samples - McNemar test
  • Put one of the two paired variables in the box below Rows and the other paired variable in the box below Columns
Regression > 2 Outcomes - Binomial
  • Put your dependent variable in the box below Dependent Variable and your independent variables of interval/ratio level in the box below Covariates
  • If you also have code (dummy) variables as independent variables, you can put these in the box below Covariates as well
  • Instead of transforming your categorical independent variable(s) into code variables, you can also put the untransformed categorical independent variables in the box below Factors. Jamovi will then make the code variables for you 'behind the scenes'
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